In Vitro Synergy of Levofloxacin Plus Piperacillin/Tazobactam against Pseudomonas aeruginosa

نویسندگان

  • Vladimir Chachanidze
  • Aixa Curbelo-Irizarry
  • Deborah Ashcraft
  • George Pankey
چکیده

In vitro synergy testing using levofloxacin (LVX) plus piperacillin/tazobactam (TZP) was performed by Etest and time-kill assay (TKA) for 31 unique fluoroquinolone-resistant Pseudomonas aeruginosa isolates. The Etest method showed synergy for 9/31 (29%) of isolates, while TKA showed synergy with 14/31 (45%) of isolates. When comparing the Etest method and TKA, concordant results for synergy, antagonism, and indifference were obtained for 24/31 (77%) of the isolates tested.

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عنوان ژورنال:

دوره 2009  شماره 

صفحات  -

تاریخ انتشار 2009